资生堂

资生堂液相色谱系统的开发起源于上世纪80年代承担的一项开发生体样品中痕量物质检测方法的日本国家攻关项目，其技术设计的的出发点就是为了消除物质在固定相表面由于金属不纯物和游离硅羟基引起的“二次保留”而造成的峰形拖尾和死吸附，从而最大限度地提高痕量物质检测感度和准确性。为了这个目的，资生堂将制作化妆品的粉体表面处理技术应用于色谱柱填料生产，采用独有的高分子包被技术，研制出高分子包被的“胶囊型（capsule type）”色谱填料，完全突破了以往制造工艺的技术瓶颈，从根本上解决了通常色谱柱端基键合封尾不完全对色谱分离所造成的影响。自1987年开发出来划时代的高分子包被型ODS柱（AG）以来，通过不断改进二氧化硅基材和高分子包被技术来提高生产工艺，并开发出了世界上最高品质的MGⅡ、MG、UG、ACR、AQ、DD等新品种，从而形成了资生堂CAPCELL PAK系列高品质色谱柱，其凭借卓越的分离性能、极低的柱流失、超强的耐受性和稳定性，得到了世界上的从事HPLC分析专业的各位朋友的厚爱。

HPLC（高效液相色谱）作为一种分离、分析的重要方法得到了广泛的应用。对这种方法来说，色谱柱填料的特性会对结果产生很大的影响。资生堂为了满足各位客人对各个领域的不同要求，准备了从低极性、中极性到高极性全领域各种各样填料的柱型。资生堂CAPCELL PAK系列液相色谱柱品种规格齐全，规格上包括：预柱、适合LC-MS高感度分析的细径柱、常规分析柱和半制备、制备色谱柱。填料种类包括：反相C18、C8、C4、C1；正相NH2、CN、SCX、SILICA；应用于二维色谱分析的混合填料色谱柱CR（SCX+C18）；糖分析专用柱；手性柱CD-Ph、RU-1、RU-2；蛋白、多肽分析柱、耐酸柱、耐水柱、还原柱、前处理柱等。

资生堂以药房起家，最初并非化妆品公司。1872年，曾留学海外攻读药剂，并曾为日本海军药剂部主管的福原有信(Yushin Fukuhara)，在东京银座开设自己的药房，名为资生堂，这亦是全日本第一间西式药房。除了卖药，福原有信也有自己制药，及至1888年，他成功研制了全日本的第一瓶牙膏，迅即取代了当时流行的洁牙粉，亦令资生堂成为日本本土为人熟悉的名字。牙膏这概念沿自西方的，而牙膏瓶亦印上了汉字和英文字，预告一个结合着东西方文化的故事即将诞生。

直至1897年，资生堂创制出Eudermine(希腊文，是good和skin的意思)。这是一支突破性的美颜护肤化妆水——酒红色的化妆水，为资生堂开始了踏入化妆界的第一页。 到了福原有信的儿子福原信三(Shinzo Fukuhara)上场，资生堂经营情况才开始改变。信三曾游历欧美多国，对当地美学和文化极有心得。1916年，他成立资生堂的设计部门，专责产品包装和宣传。自此，他们以富有独特装饰艺术风格的字母来设定资生堂这名字的外貌，并以山茶花作公司标志，再加上富有阿拉伯色彩的花叶阔形来装饰产品瓶身。资生堂的品牌形象，自此可算有了雏形。虽然，时至今日，山茶花和阿拉伯图纹已不复存在，资生堂的字体亦曾两度修改，但现时所见的“Shiseido”字样，亦与当年的非常相似。

1918-1921年，来自菊花、紫藤、洋李和夜来香等日本花卉的灵感促使资生堂开发了第一款为公司建立香氛声誉的香水。无论是香水本身还是香水瓶身典雅的设计都散发着独特永久的魅力，时至今日，资生堂已经成为全世界香氛领域的选择。

1923年，资生堂开展连锁经营模式，加强作全国性的宣传，形象亦同时变得更加鲜明。到1948年，信三逝世，由他的侄儿福原义春接手，第三代的家族继承人上场，又开拓了新的一番事业。于1957年，资生堂开始开发国外市场，打头炮的是在1965年推出的Zen香水，而1978年推出的Moisture Mist化妆品系列，包装构思乃取材自日本红漆器。其间，资生堂另外推出的各色化妆品、香氛及护肤系列，却彻底地国际化，选用了充满西方味道的包装。

到了近年，对资生堂形象影响最深远的，则必定是Sorge Lutens了。这位出生于法国的形象设计师，自1980年开始，成为了资生堂的形象设计师，深深影响了此品牌的化妆品系列。他创制的女性形象，都似真还假、既虚无又实在，结合了东方及西方的美，这也正是资生堂的所塑造的女性形象。

The development of Shiseido liquid chromatography system originated from a Japanese national research project undertaken in the 1980s to develop the detection method of trace substances in biological samples. The starting point of its technical design is to eliminate the peak tailing and dead adsorption caused by the "secondary retention" of substances on the surface of stationary phase caused by metal impurities and free silicon hydroxyl groups, So as to maximize the sensitivity and accuracy of trace substances detection. For this purpose, Shiseido applied the powder surface treatment technology for making cosmetics to the production of chromatographic column filler, and developed a polymer coated "capsule type" chromatographic filler by using the unique polymer coating technology, which completely broke through the technical bottleneck of the previous manufacturing process, It fundamentally solves the influence of incomplete end group bonding and tail sealing on chromatographic separation. Since the epoch-making polymer coated ODS column (Ag) was developed in 1987, the production process has been improved through continuous improvement of silica substrate and polymer coated technology, and the world's highest quality mg Ⅱ, Mg, UG, ACR, AQ, DD and other new varieties have been developed, thus forming Shiseido capcell Pak series high-quality chromatographic columns. With excellent separation performance Extremely low column loss, strong tolerance and stability have been loved by friends engaged in HPLC analysis in the world.

HPLC (high performance liquid chromatography) has been widely used as an important method for separation and analysis. For this method, the characteristics of chromatographic column packing will have a great impact on the results. In order to meet the different requirements of guests in various fields, Shiseido has prepared a variety of column types of fillers from low polarity, medium polarity to high polarity. Shiseido capcell Pak series liquid chromatographic columns have complete varieties and specifications, including pre column, fine diameter column suitable for LC-MS high sensitivity analysis, conventional analytical column, semi preparation and preparation column. The types of fillers include: inverted C18, C8, C4 and C1; Normal phase NH2, CN, SCX, silica; Mixed packing chromatographic column Cr (SCX + C18) for two-dimensional chromatographic analysis; Special column for sugar analysis; Chiral columns cd-ph, RU-1, ru-2; Protein and polypeptide analysis column, acid resistant column, water resistant column, reduction column, pretreatment column, etc.

Shiseido started as a pharmacy, not a cosmetics company at first. In 1872, Yushin Fukuhara, who studied abroad to study pharmacy and was the director of the Pharmaceutical Department of the Japanese Navy, opened his own pharmacy in Ginza, Tokyo, called Shiseido, which is also the first Western pharmacy in Japan. In addition to selling medicine, Fukuhara Youxin also had his own medicine. In 1888, he successfully developed the first bottle of toothpaste in Japan, which immediately replaced the popular tooth cleaning powder at that time, and made Shiseido a familiar name in Japan. The concept of toothpaste comes from the west, and the toothpaste bottle is also printed with Chinese characters and English characters, which heralds the birth of a story combining Eastern and Western cultures.

Until 1897, Shiseido created eudermine (Greek, which means good and skin). This is a breakthrough beauty and skin care Toner - wine red toner, which has started the first page of Shiseido's entry into the makeup industry.

It was only when Shinzo Fukuhara, fuhara's son, came on stage that Shiseido's business began to change. Shinsan has traveled to many countries in Europe and America and has great experience in local aesthetics and culture. In 1916, he established the design department of Shiseido, which was responsible for product packaging and publicity. Since then, they have set the appearance of the name Shiseido with letters rich in unique decorative art style, and decorated the bottle body with Camellia as the company logo, plus the broad shape of flowers and leaves rich in Arabic color. Shiseido's brand image has taken shape since then. Although camellia and Arabic patterns no longer exist today, and Shiseido's font has been modified twice, the word "Shiseido" seen now is also very similar to that of that year.

In the 1918-1921 year, inspiration from Japanese flowers, such as chrysanthemum, wisteria, Yang Li and evening primrose, prompted Shiseido to develop the first perfume to create a fragrance for the company. Whether the perfume itself or perfume bottle elegant design has unique and lasting charm, today, Shiseido has become the world's choice of fragrance field.

In 1923, Shiseido launched the chain operation mode and strengthened national publicity, and its image became more distinct at the same time. By 1948, Shinzo died and was taken over by his nephew Yichun Fukuhara. The third generation of family heirs came on and opened up a new career. In 1957, Shiseido began to develop foreign markets. The first Zen was launched in 1965, and the Moisture Mist cosmetics series introduced in 1978 was made from Japanese red lacquer ware. Meanwhile, Shiseido has also launched various cosmetics, fragrances and skin care series, but they are completely internationalized and choose packaging full of Western flavor.

In recent years, Sorge Lutens must have the most far-reaching impact on Shiseido's image. The French born image designer has become the image designer of Shiseido since 1980, which has deeply influenced the cosmetics series of this brand. The female images he created are both true and false, both nihilistic and real, combined with the beauty of the East and the west, which is the female image created by Shiseido.